Jamie Harper was last seen on the morning of Saturday, March 10, 2007, at approximately 4:30 a.m. She had attended a party the previous evening in Rantoul, Illinois, and had made plans to spend the night at a friend's house. She never arrived at the friend's house and never returned home. All of her possessions, including her epilepsy medication, were left at her residence. Harper has a pierced nose and a tattoo of a tribal design on her back. She was last seen wearing a white jacket, blue jeans, and sandals, and was carrying a black handbag.

Individuals with information concerning this case should take no action themselves, but instead immediately contact the nearest FBI Office or local law enforcement agency. For any possible sighting outside the United States, contact the nearest United States Embassy or Consulate.